A pioneering study has provided unprecedented insights into the immune response following pig-to-human kidney xenotransplantation.1 The findings, presented today at the ESOT Congress 2025, mark a significant step forward in overcoming the biggest challenge in xenotransplantation: rejection by the human immune system. Using cutting-edge spatial molecular imaging, researchers mapped how human immune cells interact with…
Previously described as playing astronomical ‘spot the difference,’ Kilonova Seekers asks the public to compare the latest images of a section of night sky to an image of the same section of space taken on previous nights. Their goal – to spot new stars or significant changes in light intensity that may indicate that something…
Phoebe Waller-Bridge has worked on some unusual projects since Fleabag, the comedy-drama that made her name and broke many a heart. Octopus!, a two-part documentary on Amazon Prime Video about (you guessed it) octopuses, may just be the oddest one yet. That exclamation mark is an omen of the whimsy to come – this is…
What’s missing? Pondering the displays at the American Museum of Natural History in New York City Jeffrey Greenberg/Universal Images Group via Getty Images Nature’s MemoryJack Ashby (Allen Lane) Museums are strange things, Jack Ashby, assistant director of the University Museum of Zoology in Cambridge, UK, points out in his new book, Nature’s Memory: Behind the…
An orca attempting to share food with a researcher holding a camera Orca Research Trust Orcas have been seen appearing to gift dead prey to humans, which may be a sign that they engage in altruism and can recognise sentience in other species. Jared Towers at marine research firm Bay Cetology was filming a pod…
Urea is one of the most important industrial chemicals produced worldwide. It is used as a fertiliser, for the production of synthetic resins and explosives and as a fuel additive for cleaning car exhaust gases. Urea is also believed to be a potential key building block for the formation of biological molecules such as RNA…
A team of researchers from the Keck School of Medicine of USC’s Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) has identified a new brain imaging benchmark that may improve how researchers classify biologically meaningful changes associated with Alzheimer’s disease, especially in Hispanic and non-Hispanic White populations. The new study, published in Imaging…
PTEN Connection to Autism: Up to 25% of those with brain overgrowth and autistic spectrum disorder (ASD) carry variations in a gene called PTEN; PTEN-deficient mouse models exhibit ASD-like characteristics Cell-type Specific Model: PTEN loss in specific neurons leads to circuit imbalance and altered behavior Excitation-Inhibition Imbalance: Strengthened excitatory drive and loss of local inhibitory…
India’s population is genetically one of the most diverse in the world, yet it remains underrepresented in global datasets. In a study publishing in the Cell Press journal Cell, researchers analyzed genomic data from more than 2,700 people from across India, capturing genetic variation from most geographic regions, linguistic groups, and communities. They found that…
Vance Holliday jumped at the invitation to go do geology at New Mexico’s White Sands. The landscape, just west of Alamogordo, looks surreal – endless, rolling dunes of fine beige gypsum, left behind by ancient seas. It’s one of the most unique geologic features in the world. But a national park protects much of the…
