Researchers at Leipzig University and Charité – Universitätsmedizin Berlin have discovered a key mechanism for appetite and weight control. It helps the brain to regulate feelings of hunger. In a study, scientists from Collaborative Research Centre (CRC) 1423 – Structural Dynamics of GPCR Activation and Signaling – found how a protein called MRAP2 (melanocortin 2…
A key switch for cellular energy balance has been discovered in cells: it could potentially become the target of new therapies for diseases ranging from Parkinson’s to rare disorders caused by defects in the cell’s powerhouses, the mitochondria. The switch is called phosphatase B55 (PP2A-B55alpha) and regulates the balance of mitochondria. Experts from Università Cattolica,…
A higher weekly dose of semaglutide (7.2 mg) can significantly improve weight loss and related health outcomes in adults living with obesity, including those with type 2 diabetes (T2D), according to the results of two large-scale, international phase 3 clinical trials. The findings, published in The Lancet Diabetes & Endocrinology journal, suggest that a higher…
Drinking any amount of alcohol likely increases the risk of dementia, suggests the largest combined observational and genetic study to date, published online in BMJ Evidence Based Medicine. Even light drinking — generally thought to be protective, based on observational studies — is unlikely to lower the risk, which rises in tandem with the quantity…
The habitat of thirty species of sharks, rays, and chimaeras, also called ghost sharks, overlap with areas where proposed deep-sea mining may occur, according to new research published in Current Biology and led by University of Hawai’i at Mānoa oceanographers. Nearly two-thirds of these species are already threatened with extinction due to human impacts, so…
Published October 4, 2025 Jordan Brand is bringing its flagship retail concept to the United States, with the opening of its first U.S. ‘World of Flight’ location in Philadelphia on October 10. Jordan Brand to open first U.S. World of Flight flagship in Philadelphia. – Jordan Brand Located at 1617 Walnut Street, World of Flight…
Published October 4, 2025 Pharrell Williams will be honored with the 2025 André Leon Talley Lifetime Achievement Award by the Savannah College of Art and Design (SCAD). Pharrell Williams named 2025 André Leon Talley Lifetime Achievement Award winner. – Pharrell Williams The award recognizes Williams’ groundbreaking contributions to fashion and his influence across music, film,…
Published October 4, 2025 Timberland and Telfar have teamed up to launch a capsule collection that reimagines the classic Yellow Boot while expanding into bags. Timberland and Telfar launch capsule collection. – Timberland x Telfar At the center of the collection is the Timberland x Telfar Tall Pull-On Boot, a 26-inch unstructured style in pebbled…
Published October 5, 2025 Discontent had been simmering around the historic Parisian department store on Rue de Rivoli. The announcement that Shein would take a floor in November further widened the rift between brands and management. For months, BHV’s brands and suppliers have been grappling with unpaid invoices owed by the management of the department…
Published October 5, 2025 After her performative happening at Palacete Gomes Freire last Thursday, October 2, as part of Lisbon Fashion Week, Ana Margarida Feijão is preparing to present her collection titled “Liberdade é Nome de Mulher” (Freedom is a Woman‘s Name) next Thursday, October 9, in an exhibition of “wearable sculptures that fuse fashion,…
